One challenge for development of non toxic micro-CT contrast agents is to load a high concentration of an X-ray attenuating element in a nanoparticulate formulation with particle size distribution small enough to avoid accumulation in lungs but large enough to avoid kidney filtration. Binitio Biomedical’s Exia 160 and Exia 160XL meet these requirements with sufficient stealth properties for vascular imaging. In addition, they are made of components which are metabolized by catabolic pathways in the body thus enabling metabolic imaging of the myocardium and brown adipose tissue.
“Tissue clearing” isn’t one product — it’s a small ecosystem of reagents and, in Binaree’s case, an optional automated system built around it. Choosing the
Designing a rigorous behavioral experiment is only half the challenge. Making it run reliably, trial after trial, session after session, is where most labs lose
