Introducing CJ215 Fluorescent Dye for NIR/SWIR Pan-Cancer Imaging

We are thrilled to announce that CJ215, a tumor labeling dye, is now available through MediLumine. Developed by ProImaging (Paris, France), CJ215 is making waves in cancer research, offering exceptional performance in Near-Infrared (NIR) and Short-Wavelength Infrared (SWIR) imaging applications.

Cancer research requires highly specialized tools to accurately identify and visualize tumors across various models. CJ215 has been validated across multiple tumor types, including breast, pancreatic, prostate, colon, and fibrosarcoma, making it one of the most versatile imaging dyes available today.

CJ215 is specifically designed to bind to tumor tissues, enabling researchers to obtain precise, reliable visualization in a variety of cancer models. Whether you’re studying breast cancer, pancreatic tumors, or other types, CJ215 ensures consistent, high-quality results.

Purchase CJ215 through MediLumine

CJ215 is now available for purchase through MediLumine, providing researchers with a robust, high-performance option for cancer imaging studies. Visit the CJ215 product page to learn more about its applications and how it can contribute to your research.

Exceptional NIR and SWIR Performance

With its optimized absorption at 800 nm and emission at 825 nm, CJ215 delivers superior imaging results, particularly in NIR and SWIR applications. This allows researchers to achieve deeper tissue penetration and clearer imaging with reduced background noise, making CJ215 ideal for advanced cancer imaging studies.

Advanced Fluorescence Imaging

CJ215’s ability to bind directly to tumor tissues facilitates precise fluorescence imaging. This level of accuracy is critical in identifying cancerous tumors, distinguishing them from surrounding healthy tissues, and advancing our understanding of tumor biology.

Technical Specifications of CJ215

• Max Absorption: 800 nm
• Max Emission: 825 nm
• Storage: Stable for 12 months at -20°C, protected from light
• Molecular Weight: ~1330
• Solubility: Isotonic Dextrose Solution
• Shipping Condition: Room temperature for up to 3 weeks

Highlighted citation with CJ215

In a recent Nature Biomedical Engineering article, CJ215 was used for real-time tumor visualization across multiple cancer types, including breast, prostate, colon, fibrosarcoma, and colorectal metastasis. CJ215 is sensitive to apoptosis and has absorption and emission spectra suitable for near-infrared (NIR) and shortwave infrared (SWIR) imaging, enabling high-contrast tumor delineation with tumor-to-muscle ratios reached up to 100, and tumor-to-liver ratios reached up to 18.

Full citation

Mc Larney B, Sonay A, Apfelbaum E, Mostafa N, Monette S, Goerzen D, Aguirre N, Isaac E, Phung N, Skubal M, Kim M, Ogirala A, Veach D, Heller D, Grimm J. A pan-cancer agent for screening, resection and wound monitoring via NIR and SWIR imaging. Res Sq [Preprint]. 2024 Jan 23:rs.3.rs-3879635. doi: 10.21203/rs.3.rs-3879635/v1. Update in: Nat Biomed Eng. 2024 Sep;8(9):1092-1108. doi: 10.1038/s41551-024-01248-w. PMID: 38343820; PMCID: PMC10854300.