Bradykinin B1 Receptor Antagonist (R-954)


R-954 (AcOrn[Oic(2),(αMe)Phe(5),dβNal(7),Ile(8)]desArg(9)-bradykinin) is an antagonist peptide of the bradykinin B1 receptor. MediLumine has a commercial license for sale of this peptide developed by Dr. Pierre Sirois and Dr. Fernand Gobeil Jr. at the University of Sherbrooke, Quebec Canada.  It is used for for research into pain syndromes, cancer, pain associated with diabetes mellitus, inflammation, different types of vasculopathies, angiogenesis, multiple sclerosis, epilepsy, alzheimer disease, arthritis and various other disease states.


  • Sequence: NH2-Sar-Lys-Arg-Pro-Pro-Gly-Phe-Ser-Pro-(D-Phe)-COOH
  • Over 98% pure as measured by HPLC and Mass spectrometry

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