Description
Product Overview
ExiTron™ nano 12000 is a nanoparticle based CT contrast agent optimized for high resolution angiography in preclinical studies. As a complementary agent to ExiTron™ nano 6000, it also supports liver imaging and detection of hepatic tumors and metastases. Its formulation combines prolonged intravascular retention with the ability to traverse fenestrated vessels, enabling comprehensive cardiovascular and oncological imaging in a single session. Ordering through an authorized distributor ensures access to technical support, validated logistics, and compliant supply.

Intended Use and Imaging Rationale
High resolution CT angiography requires stable vascular enhancement over extended periods to capture fine vascular structures. ExiTron™ nano 12000 maintains a steady blood pool, enabling detailed imaging of microvessels while also passing through fenestrated vessels in tumors and inflamed tissues. This dual functionality allows simultaneous assessment of vasculature and liver pathology in small animal models.
Imaging Characteristics and Vascular Applications
Following administration, ExiTron™ nano 12000 provides strong and prolonged contrast enhancement of the vascular system. The long steady state allows high resolution imaging of the heart and microvasculature, while liver uptake facilitates detection of hepatic lesions. These properties support longitudinal studies and 3D volume rendering workflows.

Applications in Preclinical Research
ExiTron™ nano 12000 is applied in micro CT studies for quantitative vascular analysis, assessment of tumor and inflammation associated vascular abnormalities, liver imaging, and longitudinal monitoring of disease progression. Its prolonged circulation time ensures flexibility in acquisition timing and compatibility with advanced reconstruction methods.
Physicochemical and Technical Properties
ExiTron™ nano 12000 consists of uniform nanoparticles engineered for vascular and liver imaging. The mean hydrodynamic diameter is approximately 110 nanometers. Undiluted X ray attenuation reaches approximately 12,000 Hounsfield units, providing high contrast for detailed preclinical angiography.
Preclinical Imaging Validation
CT angiography studies demonstrate clear visualization of cardiac and extracranial vasculature. Longitudinal imaging confirms stable vascular enhancement, supporting reproducible quantitative analysis and assessment of liver and spleen structures over time.
Scientific References
ExiTron™ nano 12000 has been validated in peer reviewed studies covering micro CT analysis of vasculature and organs, tumor angiography, aortic aneurysm and dissection measurement, and longitudinal liver and spleen imaging in mouse models.
Ordering and Distribution Information
ExiTron™ nano 12000 is available in single and multiple injection formats, including one set of five injections or five sets of five injections. Ordering through an authorized distributor provides local availability, institutional purchasing support, and access to technical resources.
Documentation and Technical Resources
Supporting materials include a detailed product data sheet, application sheets for longitudinal tumor angiography, left ventricular volume estimation, lung adenocarcinoma progression monitoring, and technical notes on 4D cardiac-respiratory gated CT and high resolution in vivo micro CT of vasculature.
Authorization Statement
Authorized distributor of Viscover products by Nanopet Pharma GmbH. This page contains original distributor specific content intended to support preclinical CT angiography and liver imaging research.




