Mbio Cycluc1 is ready to use luciferin analog ideal for in vivo imaging. It can be administered via intravenous (i.v.), subcutaneous (s.c.), or intraperitoneal (i.p.) injections. The product gives a luminescence peak at 620 nm (orange to red window) when used with the standard firefly luciferase reporter system. This enables deeper and more sensitive tissue imaging due to the reduced absorption and scattering of light compared to photonic emissions of D-Luciferin. The analog also provides stronger emissions for in vitro assays compared to the use of D-Luciferin.
- Composition: Sodium (4S)-2-(6,7-dihydro-5H-thiazolo[4,5-f]indol-2-yl)-4,5-dihydro-thiazole-4-carboxylate in PBS (magnesium and calcium free)
- Purity: 98% by HPLC
- Reference publication: Kuchimaru T, et al. Nat Commun. 2016 Jun 14;7:11856. doi: 10.1038/ncomms11856. PubMed PMID: 27297211; PubMed Central PMCID: PMC4911627.