Alpha-Tocopheryl 2,3,5-Triiodobenzoate

Description

Alpha-Tocopheryl 2,3,5-Triiodobenzoate is a on non-toxic lipophilic molecule (alpha-tocopherol) with a high ratio of iodinated contrasting material (tri-iodobenzene). It was developed in the laboratory of Dr. Vandamme at the University of Strasbourg and is the main ingredient of the Fenestra HDVC contrast agent used for vascular imaging, functional and anatomical imaging, staging and monitoring fatty liver disease, quantifying liver tumor burdens. Fenestra HDVC remains in liver for many months after a single injection and enabling longitudinal studies of liver diseases. 

Reference publication

Xiang Li, Nicolas Anton, Guy Zuber, Minjie Zhao, Nadia Messaddeq, François Hallouard, Hatem Fessi, Thierry F. Vandamme, Iodinated α-tocopherol nano-emulsions as non-toxic contrast agents for preclinical X-ray imaging, Biomaterials, Volume 34, Issue 2, 2013, Pages 481-491.

Properties

• Purity of 99+ % (HPLC, 215 nm)
• MW 918.50