Description
Product Overview
PolySon™ H is an ultrasound contrast agent composed of highly stable microbubbles specifically designed for liver imaging. Its formulation is optimized for high acoustic pressures, supporting stimulated acoustic emission (SAE) imaging with inducible bubble rupture using high-energy ultrasound beams.

Research Applications
PolySon™ H enables detailed visualization of liver morphology, detection of individual particles using sensitive particle acoustic quantification (SPAQ) techniques, and application of high mechanical index SAE imaging. It is particularly suitable for studies requiring high-resolution liver imaging and microbubble-based contrast assessment.
Imaging Characteristics
The agent delivers consistent contrast across a wide range of ultrasound frequencies, including frequencies above 30 MHz. Its robust microbubble structure ensures reliable imaging under high acoustic pressures and during repeated scans.
Advantages for Preclinical Liver Imaging
PolySon™ H offers reproducible liver imaging with high sensitivity for single-particle detection and controlled acoustic emission. Its microbubble stability allows longitudinal studies and advanced ultrasound imaging applications such as SAE and SPAQ.
Physico-Chemical Properties
The microbubbles have a number-weighted particle size of 1-3 µm. This size distribution supports effective circulation in the liver vasculature and optimal acoustic response.
Preclinical Imaging Validation
Stimulated acoustic emission imaging with PolySon™ H demonstrates pseudo-doppler effects as individual microbubbles rupture, visualized with false-color mapping to indicate liver morphology and microbubble dynamics.
Ordering and Distribution
PolySon™ H is available in single or multiple injection packs. Ordering through an authorized distributor provides access to technical support, local availability, and guidance for preclinical ultrasound studies.
Authorization Statement
Authorized distributor of Viscover products by Nanopet Pharma GmbH. This page provides original distributor-specific content for preclinical liver imaging using PolySon™ H.

