Vascupaint Silicone Rubber Injection Compounds (Lead Free)


Vascupaint™ lead-free silicone injection compounds fill and opacify microvasculature structures for visual inspection (following alcohol based tissue clearing) or 3D imaging with brightfield microscopy, micro-CT, or fluorescence imaging. The injection compounds are available in many different colors including yellow which also allows micro-CT imaging. We recommend our green or blue Vascupaint for tissue clearing experiments. Other colors are available upon request.

Vascupaint™ is a less viscous alternative to conventionally used lead-based compounds making it easier to perfuse non-surviving organisms as well as human organs for ex vivo 3D vascular cast analysis.

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The 3D reconstructed images were obtained from microCT images acquired with scans at a resolution of 6 microns on a SkyScan 1276 imaging system. Brain organs were harvested following perfusion with MediLumine’s Vascupaint™ yellow silicone injection compound containing X-ray attenuating bismuth pigments. Courtesy of Dr. Sean Marrelli (UT Health) and Bruker Preclinical Imaging (Billerica, MA)

Brightfield microscopy image of murine brain vasculature following perfusion with Vascupaint yellow is courtesy of Sean Marelli, Department of Neurology, McGovern Medical School at UTHealth, Houston, TX.



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