Vascupaint Silicone Rubber Injection Compounds (Lead Free)

Description

Vascupaint™ lead-free silicone injection compounds fill and opacify microvasculature structures for visual inspection (following alcohol based tissue clearing) or 3D imaging with brightfield microscopy, micro-CT, or fluorescence imaging. The injection compounds are available in many different colors including yellow which also allows micro-CT imaging. We recommend our green or blue Vascupaint for tissue clearing experiments. Other colors are available upon request.

Vascupaint™ is a less viscous alternative to conventionally used lead-based compounds making it easier to perfuse non-surviving organisms as well as human organs for ex vivo 3D vascular cast analysis.

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The 3D reconstructed images were obtained from microCT images acquired with scans at a resolution of 6 microns on a SkyScan 1276 imaging system. Brain organs were harvested following perfusion with MediLumine’s Vascupaint™ yellow silicone injection compound containing X-ray attenuating bismuth pigments. Courtesy of Dr. Sean Marrelli (UT Health) and Bruker Preclinical Imaging (Billerica, MA)

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