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Fenestra LC


Fenestra LC iodinated nanoemulsions are used for small animal liver and spleen imaging. The modified vitamin E based lipid spheres in the Fenestra LC emulsions mimic the structure of endogeneous chylomicron remnants thus targeting hepatocytes and other soft tissue structures like pancreatic tumors. The microCT contrast agent is used for for functional and anatomical imaging, staging and monitoring fatty liver disease, quantifying liver tumor burdens.

Sweeney N, Marchant S, Martinez JD. Intraperitoneal injections as an alternative method for micro-CT contrast enhanced detection of murine liver tumors. Biotechniques. 2019 May;66(5):214-217. doi: 10.2144/btn-2018-0162.

Seo Y, Craig MC, Murphy ST, Feng J, Chen X, Yuneva M. [18F]-(2S,4R)4-Fluoroglutamine PET Imaging of Glutamine Metabolism in Murine Models of Hepatocellular Carcinoma (HCC). Mol Imaging. 2022 Jul 25;2022:5185951. doi: 10.1155/2022/5185951.

Zhu G, Sun H, Wang J, Zhao Z, Bao J, Feng R, Zhou J, Jing Z. In Vivo Detection and Measurement of Aortic Aneurysm and Dissection in Mouse Models Using Microcomputed Tomography with Contrast Agent. Contrast Media Mol Imaging. 2019 Mar 6;2019:5940301. doi: 10.1155/2019/5940301.

Mogler C, König C, Wieland M, Runge A, Besemfelder E, Komljenovic D, Longerich T, Schirmacher P, Augustin HG. Hepatic stellate cells limit hepatocellular carcinoma progression through the orphan receptor endosialin. EMBO Mol Med. 2017 Jun;9(6):741-749. doi: 10.15252/emmm.201607222. 


SKU: LC-131 Categories: ,
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