MediLumine’s PRISM™ SWIR In Vivo Imaging System opens new possibilities in molecular imaging by resolving biomarkers deep in living tissue. Imaging in the shortwave infrared, where tissue scatters far less light and emits far less autofluorescence than in the visible or NIR range, delivers deeper penetration, lower background, and higher contrast at depth. The result is clean signal from targets that are difficult or impossible to resolve with conventional imaging.
The system captures NIR-II and SWIR emission from a wide range of probes, including the long wavelength tail of established dyes like Cy5, Cy7.5, and IRDye800CW, as well as dedicated SWIR emitters, so researchers can bring existing labels into the SWIR window or adopt purpose built SWIR agents.
Excitation is fully modular, accepting up to four external laser illumination modules across the NIR and SWIR range (for example 670, 785, 890, 980, and 1076 nm), so the excitation set can match the probes in use and expand as a program grows. Auto laser and auto exposure modes tune each capture for optimal depth and contrast without manual iteration.
From real time biomarker tracking to excitation multiplexed imaging, PRISM SWIR gives preclinical researchers a powerful, straightforward path to the sensitivity and depth of shortwave infrared imaging.
