Ratiometric FRET Fiber Photometry System

Description

The Fiber Photometry System is an ideal solution for in vivo studies of brain activity in freely moving rodents, such as mice and rats. It features Fluorescence Resonance Energy Transfer (FRET) for high sensitivity of ratiometric biosensors, ensuring precise and reliable measurements. This system is designed to provide robust data on neural activity, making it an essential tool for neuroscience research.

We offer a wide selection of lasers and optical filters for commercially available biosensors or your own developed fluorescent biosensors. Also available for intensiometric biosensors via conventional fluorescence with a reflectance correction channel. Optical filter sets and laser sources are user-replaceable for increased modularity.

Increase throughput with our 4-channel version, enabling simultaneous monitoring of multiple subjects or regions. Each channel operates independently with its own set of PMT detectors, requiring no calibration or alignment.

Additionally, the system includes up to 8 analog inputs that can be used as input triggers to start recording or for synchronization with other devices. Finally, The software displays the FRET ratios, ΔF/F to measure ratio changes compared to a baseline, and supports recording protocols to run a series of multiple acquisitions.