Bright Instruments is a UK-based manufacturer with more than 80 years of heritage in precision cryostat and microtome manufacturing. Trusted by pharmaceutical companies, CROs, and academic institutions worldwide, their instruments are renowned for reliability, sectioning accuracy, and engineering quality. Every machine is made in Britain and backed by hands-on service and technical support.
As a company already embedded in the preclinical radiolabelled compound space — offering the complete suite of CRO services — MediLumine is uniquely positioned to support your entire workflow: from radiolabelling and imaging to the sectioning and tissue analysis, to imaging fluorescent biodistribution of conventional fluorophores with the PRISM SWIR imaging system.
The centrepiece of the Bright lineup for preclinical work is the 9400 Whole Small Animal Cryostat, a patented instrument specifically engineered for whole-body frozen sectioning of small animals. It is the only instrument of its kind protected under Global Patent GB1803310.0.
The 9400 produces high-quality, reproducible whole-body frozen sections of mice, rats, guinea pigs, and rabbits. With sections as thin as 1 µm and a specimen window accommodating animals up to 400 mm long, it delivers the anatomical fidelity and molecular integrity that autoradiography, toxicology, and biodistribution studies demand. A dual compressor refrigeration system maintains chamber temperature down to -35°C, while a touchscreen interface and programmable batch slicing modes keep the workflow efficient even at high throughput.
The 9400 supports a broad range of preclinical research applications where whole-organism spatial data is essential:
Because sectioning preserves anatomical fidelity across all organs simultaneously, researchers gain a systemic view of compound distribution that isolated organ sampling cannot provide.
Pharmaron, one of the world’s leading contract research organisations for radioisotopically labelled studies, selected the 9400 to support their growing portfolio of drug biodistribution studies at their Northamptonshire facility. Their team cited the instrument’s sectioning consistency, the hands-free knee switch operation, and the quality of Bright Instruments’ ongoing service and support as decisive factors.
A high-throughput bench cryostat for busy preclinical labs, featuring exceptional temperature stability, a built-in UV decontamination system for contamination control, and an energy-saving sleep mode. Suited to labs processing large volumes of tissue on a regular basis.
Precision rotary sectioning down to 0.5 µm for histopathological analysis of paraffin-embedded samples and surgical biopsies. Reliable and precise, for labs where section quality is non-negotiable.
Our team is available to walk you through each system and help identify the right fit for your preclinical program. Whether you are establishing a whole-body autoradiography capability for the first time or looking to upgrade your current sectioning workflow, we are here to help.
Bright Instruments is a UK-based manufacturer with more than 80 years of heritage in precision cryostat and microtome manufacturing. Trusted by pharmaceutical companies, CROs, and
In the field of preclinical phenotyping, the ability to obtain high-resolution skeletal and soft tissue data without compromising throughput is essential. MEDIKORS has addressed this
