Latest Upgrade to the InAlyzer2 DXA System

In the field of preclinical phenotyping, the ability to obtain high-resolution skeletal and soft tissue data without compromising throughput is essential. MEDIKORS has addressed this need with the following upgrades to the InAlyzer2:

Optimized Throughput: The 28-Second Full-Body Scan

Time-efficient data acquisition is critical for large-scale studies. The InAlyzer2 features a Quick Mode capable of completing a full-body scan in 28 seconds. This high-speed acquisition minimizes the duration of anesthesia, thereby reducing physiological stress on animal subjects and improving the overall safety profile of longitudinal protocols.

Superior Spatial Resolution and Analytical Precision

Precision in body composition analysis depends on the quality of the underlying hardware. The InAlyzer2 delivers ultra-high-resolution imaging with a 99 µm pixel size (5.0 lp/mm). This level of detail allows for:

• Intricate Bone Morphometry: Clearer visualization of trabecular and cortical structures.
• Accurate Tissue Segmentation: Precise differentiation between fat mass (FAT) and lean mass (LEAN).
• High Sensitivity: Reliable detection of subtle changes in Bone Mineral Density (BMD) and Bone Mineral Content (BMC).

Technical Innovations in Stability and Software

The InAlyzer2 integrates several hardware and software advancements to ensure reproducible results:

1. Integrated Anesthesia Clamp: A newly designed fixation system stabilizes experimental animals to eliminate motion artifacts while maintaining a continuous flow of anesthetic gas.
2. Advanced Analysis Software: The platform features an intuitive interface for ROI (Region of Interest) configuration, supporting up to 30 custom ROIs for targeted tissue analysis.
3. Comprehensive Tool Kit: Researchers can simultaneously analyze BMD, FAT, and LEAN metrics in a single scan, with bulk data export capabilities to facilitate high-volume statistical processing.

Technical Specifications at a Glance

Feature	Specification
Scan Time	28 seconds (Quick Mode)
Resolution	99 µm Pixel size (5.0 lp/mm)
Beam Type	Fan Beam DXA
Scan Area	S: 140 x 210 mm / M: 210 x 315 mm
Radiation Safety	Internal lead shielding
Data Output	BMD, BMC, Fat Mass, Lean Mass, Fat Percentage

The InAlyzer2 is optimized for a variety of research domains, including osteoporosis models, metabolic disease studies, and sarcopenia research. The system’s Custom View functionality allows for sophisticated tissue color mapping, providing researchers with a visual and quantitative representation of body composition distribution.

By utilizing a True Fan-Beam technique with a 64-channel linear array detector, the InAlyzer2 eliminates the geometric distortion often found in traditional cone-beam systems, ensuring that measurements remain consistent across the entire scanning field.