FeraSpin™ T is a superparamagnetic iron oxide nanoparticulate MRI agent specifically developed for in vitro cell labeling and subsequent in vivo tracking. The agent enables efficient uptake by a wide range of cell types without the need for transfection reagents while providing strong T2/T2* contrast in MRI studies.
FeraSpin™ T is suitable for labeling stem cells, primary cells, and cell lines to monitor their migration, engraftment, and behavior in vivo. The agent facilitates investigation of cell fate, tissue integration, and mechanisms underlying regenerative or pathological processes.
The nanoparticles have a mean hydrodynamic diameter of 60 nm with a narrow size distribution, optimized for cellular uptake and stability. Relaxivity at 37 °C and 1.41 T is r1 = 8 L mmol-1 s-1 and r2 = 280 L mmol-1 s-1 in water, providing strong T2/T2* contrast for in vivo MRI visualization of labeled cells.
FeraSpin™ T allows precise cell labeling without chemical transfection, enabling longitudinal tracking of cells in small animal models. The high contrast effect supports detailed imaging of migration pathways and localization, facilitating quantitative analysis of cellular dynamics.
Axial MR images of rat brain post-injection of MSCs labeled with FeraSpin™ T demonstrate clear detection at the injection site on day 1. By days 2 and 7, labeled cells are observable at secondary locations, confirming successful in vivo tracking of cell migration.
FeraSpin™ T is available in single and multiple injection packs. Authorized distributors provide local support, technical guidance, and delivery for preclinical research applications.
Authorized distributor of Viscover products by Nanopet Pharma GmbH. Content developed for preclinical MRI cell tracking applications using FeraSpin™ T.
Price range: USD $632 through USD $2,894
