The 3000-01 Clini RF is a compact, free-standing, ultra-low temperature freezer engineered for the rapid and controlled freezing, as well as short-term storage, of tissue specimens. This system is designed to facilitate standardized pre-analytical tissue preparation, crucial for maintaining sample integrity in both clinical and research environments. By eliminating the inherent handling risks associated with cryogenic fluids, the Clini RF offers a significantly safer and highly reproducible alternative to traditional snap-freezing methods.
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Central to the Clini RF’s design are its two independently regulated cylindrical chambers, specifically engineered to optimize sample integrity throughout the freezing process. This configuration ensures reproducible freezing conditions, which is vital for minimizing variability in subsequent cryostat sectioning. The upper chamber consistently maintains a temperature of -40°C, serving as a secure short-term holding area for samples post-initial freezing to facilitate an organized workflow. Concurrently, the lower chamber provides a rapid freezing environment, reaching -80°C.
This system offers substantial flexibility in lower chamber configuration to accommodate diverse laboratory protocols and tissue handling requirements. Researchers can opt for direct tissue immersion using 3M Novec HFE 7100 fluid for efficient heat extraction. Alternatively, the chamber can be equipped with an aluminum block designed to securely hold specimen chucks or holders for controlled contact freezing, catering to a range of experimental needs.
To enhance laboratory efficiency and optimize energy consumption, the 3000-01 Clini RF incorporates an integrated seven-day programmable timer. This feature allows the system to transition into a standby mode outside of designated working hours, during which both chambers operate at -40°C to conserve power. Upon the commencement of a programmed work period, the system automatically restores normal operating parameters, with the lower chamber rapidly returning to its operational -80°C temperature.
This automated temperature management ensures the system is consistently ready for routine use while supporting energy efficiency and operational readiness. The Clini RF rapid freezing system is highly suitable for a variety of specialized laboratory applications, providing robust support for critical research and clinical workflows:
