Full Body Small Animal Sectioning System

Description

The Bright Instruments 9400 Cryostat is an advanced, high-capacity system engineered for comprehensive whole-body sectioning of small animals. Designed to address the limitations of standard cryostats, this versatile instrument facilitates complete anatomical and molecular studies while meticulously preserving multi-organ tissue integrity. It is suitable for a wide range of research and industrial sectors, including medical, histology, life sciences, toxicology, developmental biology, and material analysis. Patent: GB1803310.0

Research Applications

The 9400 Cryostat is specifically engineered to support advanced preclinical and multi-organ research across various disciplines. Its capabilities enable detailed investigations in:

• Whole Animal Sectioning: Accurately sectioning whole specimens such as mice, rats, guinea pigs, and small breed rabbits.
• Toxicology and Pharmacology: Comprehensive assessment of systemic effects, tissue distribution, and multi-organ interactions.
• Developmental Biology: Facilitating comprehensive anatomical studies and organogenesis research.
• Autoradiography Integration: Visualization of radiolabelled drug biodistribution, blood-brain barrier penetration, and tumor localization.

This whole-body cryosectioning capability ensures the preservation of molecular, cellular, and structural integrity, yielding high-quality sections essential for protein localization, gene expression analysis, and functional mapping. Furthermore, its robust design makes it suitable for material science and industrial research involving the sectioning of large, small-animal-like specimens for experimental studies.

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Key Features

The Bright Instruments 9400 Cryostat is designed with features that enhance precision, versatility, and user control in whole-body sectioning workflows.

The system incorporates a large specimen stage engineered to accommodate specimens up to 110 mm (H) x 150 mm (W) x 400 mm (L). This capability supports precise and reproducible sectioning of whole-body specimens, with section thickness adjustable in 1 µm increments from 5 µm to 200 µm.

A user-friendly touchscreen control panel provides centralized management of critical parameters, including temperature, section thickness, and batch quantities. Researchers can easily switch between single and continuous cutting modes, enabling efficient workflow customization for complex sectioning protocols.

Recognizing the diverse needs of scientific inquiry, the 9400 Cryostat offers customizable specifications. This adaptability makes it an ideal solution for core facilities conducting preclinical, multi-organ, or autoradiography studies, allowing for tailoring to individual research requirements and supporting integration with specialized accessories for temperature-controlled or unique sectioning applications.</